BRCA1-Associated Breast Cancer. Morphologically, BRCA1-associated breast carcinomas are most commonly a high-grade invasive ductal carcinoma of no special type and display minimal if any tubule or glandular formation, markedly pleomorphic nuclei (significant variation in size and shape), vesicular chromatin, prominent nucleoli, and high mitotic activity.
CASE SUMMARY: (INVASIVE CARCINOMA OF THE BREAST: Resection) Standard(s): AJCC-UICC 8 . If there are multiple invasive carcinomas, size, grade, histologic type, and the results of studies for estrogen receptor (ER), progesterone receptor (PR), and HER2 should pertain to the largest invasive carcinoma. If smaller invasive carcinomas differ any in
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